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Invited speakers

ANR2020 is proud to welcome the following invited speakers. On this page you will read there biografies and more background information, we are looking forward for their lecture. 

MARIO L. SUVA

Massachusetts General Hospital and Harvard Medical School, Boston, USA
Mario Suvà studies the biology of human brain tumors at single-cell resolution to dissect how cellular heterogeneity and plasticity contribute to tumor properties. His work established genetically and epigenetically relevant cellular models from patient tumors to identify novel therapeutic options in these dismal diseases.

Selected papers

  • Science. 2018 Apr 20;360(6386):331-335
  • Science. 2017 Mar 31;355(6332)
  • Nature. 2016 Nov 10;539(7628):309-313
  • Science. 2014 Jun 20;344(6190):1396-401
  • Cell. 2014 Apr 24;157(3):580-94
MARIO L. SUVA

RUTH H. PALMER

Institute for Biomedicine, Göteborg University, Sweden
Ruth Palmer studies basic aspects of ALK signalling using different model systems including  Drosophila melanogaster, transgenic mice, tumour-derived human cells and xenograft models. Her research led to seminal novel insights into ALK signaling, the discovery of ALK ligands and the role of ALK mutations in cancers including neuroblastoma.

Selected papers

  • Cell. 2007 Mar 9;128(5):961-75
  • PLoS Genet. 2011 Sep;7(9):e1002281
  • Elife. 2015 Sep 29;4:e09811
  • Nat Rev Cancer. 2013 Oct;13(10):685-700
Ruth Palmer

DENES HNISZ

Max-Planck Institute for Molecular Genetics, Berlin, Germany
Denes Hnisz did seminal work on core regulatory circuitries of transcription factors, super-enhancers and phase separation as postdoctoral researcher in the Rick Young lab (MIT, Boston, USA) and has recently started his own lab for the study of gene control in development and cancer in search of activation and repression of genes that specify cell identity and cancer use these insights to create therapeutic concepts for the next generation of gene control medicines.

Selected papers

  • Cell. 2013 Nov 7;155(4):934-47
  • Science. 2016 Mar 25;351(6280):1454-1458.
  • Cell. 2016 Nov 17;167(5):1188-1200.
  • Cell. 2017 Feb 9;168(4):629-643.
Hnisz

HANS CLEVERS

Hubrecht Institute, Utrecht and Director Research of the Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Hans Clevers studies the biology of Wnt signaling in tissue turnover and in cancer. His seminal discovery of Lgr5 as a generic marker of Wnt-dependent stem cells allowed to grow these stem cells into ever-expanding organoids, which hold promise in personalized drug responses and regenerative medicine.

Selected papers

  • Cell. 2019 Feb 21;176(5):1158-1173
  • Cell. 2018 Nov 29;175(6):1591-1606
  • Cell. 2015 May 7;161(4):933-45
  • Nature. 2009 May 14;459(7244):262-5
  • Nature. 2007 Oct 25;449(7165):1003-7
Hans Clevers